Functional Genomics

Thanks to large-scale international projects, a series of functional markers are continuously surveyed across human cell types and organisms. The challenge is to integrate and distribute efficiently this multi-layered data.

Transposable Elements

Transposable Elements have been associated to binding site complexes, epigenetic changes, gene expression and non-coding RNA. How to identify functional TEs from the ones creating biochemical noise?

Genome Rearrangements

Genome rearrangements can have a high functional impact but are still difficult to detect with sequencing technologies. Regions with genomic repeats are enriched in structural variants but even more challenging.

Michael Hoffman

Applications open for @Bioinfodotca course: High-Throughput Biology: From Sequence to Networks @CSHL 3/20-3/26.… twitter.com/i/web/status/8…

Meet The Lab

Guillaume Bourque

Guillaume Bourque

Principal Investigator

Director of Bioinformatics, McGill University & Genome Quebec Innovation Center

Toby Dylan Hocking

Toby Dylan Hocking

Post-Doc

Machine learning models of genomic data.

Maiko Narahara

Maiko Narahara

Post-Doc

Time-series multi-omics analysis of responses to influenza vaccines in collaboration with Kyoto University.

Jean Monlong

Jean Monlong

PhD Candidate

Copy-Number Variant Detection in Low-Mappability Regions.

Patricia Goerner

Patricia Goerner

PhD Student

Detection of L1 insertion from long-read sequencing.

Joe Su

Joe Su

Master Student

Epigenetic conservation across species and transposable elements evolution.

David Venuto

David Venuto

Undergraduate Student

Mapping functional transposable elements in primate immune cells.

News

Supervised ChIP-Seq peak annotation in Bioinformatics !

A study lead by Toby on supervised ChIP-Seq peak annotation was published today in Bioinformatics. Congrats to all the people involved ! This paper describes how visual annotations and supervised machine learning improves peak calling. More info about this...
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ESHG conference 2016

Patricia and Jean are going to ESHG in Barcelona next Month. Science with tapas by the beach !
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Canadian Human and Statistical Genetics Meeting

Patricia is going to present her poster next month for the Canadian Human and Statistical Genetics Meeting. This year it’s in Halifax !
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ICHG 2016 in Kyoto

Jean will present at the ICHG in Kyoto under the watchful eyes of Guillaume. Sugoi !
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Open Positions

The lab is currently recruiting postdocs and graduate students.

Background in programming or statistics is a must and experience in quantitative biology is a plus.

If you are interested please email your CV and the outline of a research project.

Email Us

McGill University and Genome Quebec Innovation Center

Contact

Email: Guillaume Bourque
Phone: (514) 398-7245
Fax: (514) 398-1790
Address: 740 Dr Penfield Ave, Room 6103, Montréal (Québec) H3A 1A4, Canada

 

See also